NABIL G. SEIDAH: search on Z-Library

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1

Loss-of-function PCSK9 mutants evade the unfolded protein response sensor, GRP78, and fail to induce endoplasmic reticulum stress when retained

Lebeau, Paul, Platko, Khrystyna, Al-Hashimi, Ali A, Byun, Jae Hyun, Lhoták, Šárka, Holzapfel, Nicholas, Gyulay, Gabriel, Igdoura, Suleiman A., Cool, David, Trigatti, Bernardo, Seidah, Nabil G., Austin

Journal:

Journal of Biological Chemistry

Year:

2018

Language:

english

File:

PDF, 3.36 MB

english, 2018

2

The LIM homeobox protein mLIM3/Lhx3 induces expression of the prolactin gene by a Pit-1/GHF-1-independent pathway in corticotroph AtT20 cells

Stephen E Girardin, Suzanne Benjannet, Jean-Christophe Barale, Michel Chrétien, Nabil G Seidah

Journal:

Year:

1998

Language:

english

File:

PDF, 220 KB

english, 1998

3

The ever-expanding saga of the proprotein convertases and their roles in body homeostasis

Seidah, Nabil G., Chrétien, Michel, Mbikay, Majambu

Journal:

Current Opinion in Lipidology

Year:

2018

Language:

english

File:

PDF, 305 KB

english, 2018

4

Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides

Nabil G Seidah, Michel Chrétien*,

Journal:

Year:

1999

Language:

english

File:

PDF, 1.70 MB

english, 1999

5

CORTICOTROP IN RELEASING FACTOR (CRF): EFFECTS ON THE RELEASE UF PRO-OPIOMELANOCORTIN (POMC)-RELATED PEHTIDES BY HUMAN ANTERIOR PITUITARY CELLS IN VITRO

CHAN, JOHN S.D., LU, CHAO-LIN, SEIDAH, NABIL G., CHRETIEN, MICHEL

Journal:

Year:

1982

Language:

english

File:

PDF, 373 KB

english, 1982

6

Regulation of the stepwise proteolytic cleavage and secretion of PDGF-B by the proprotein convertases

Siegfried, Geraldine, Basak, Ajoy, Prichett-Pejic, Wendy, Scamuffa, Nathalie, Ma, Liming, Benjannet, Suzanne, Veinot, John P, Calvo, Fabien, Seidah, Nabil, Khatib, Abdel-Majid

Journal:

Year:

2005

Language:

english

File:

PDF, 545 KB

english, 2005

7

Molecular cloning, characterization of cDNA, and distribution of mRNA encoding the frog prohormone convertase PC1

Gangnon, Fran�oise, Danger, Jean-Michel, Jegou, Sylvie, Vieau, Didier, Seidah, Nabil G., Vaudry, Hubert

Journal:

The Journal of Comparative Neurology

Year:

1999

Language:

english

File:

PDF, 952 KB

english, 1999

8

Arenavirus envelope glycoproteins mimic autoprocessing sites of the cellular proprotein convertase subtilisin kexin isozyme-1/site-1 protease

Antonella Pasquato, Dominique J. Burri, Esther Gomez-Ibarlucea Traba, Layane Hanna-El-Daher, Nabil G. Seidah, Stefan Kunz

Journal:

Year:

2011

Language:

english

File:

PDF, 487 KB

english, 2011

9

Dual regulation of the LDL receptor—Some clarity and new questions

Alan D. Attie, Nabil G. Seidah

Journal:

Cell Metabolism

Year:

2005

Language:

english

File:

PDF, 100 KB

english, 2005

10

Molecular evolution of the proopiomelanocortin system in Barn owl species

LÃ¶w, Karin, Ducrest, Anne-Lyse, San-Jose, Luis M., Simon, CÃ©line, Uva, Vera, Seidah, Nabil G., Pasquato, Antonella, Kunz, Stefan, Roulin, Alexandre, Vaudry, Hubert

Journal:

Year:

2020

File:

PDF, 5.04 MB

2020

11

What lies ahead for the proprotein convertases?

Nabil G. Seidah

Journal:

Annals of the New York Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 398 KB

english, 2011

12

The biology and therapeutic targeting of the proprotein convertases

Seidah, Nabil G., Prat, Annik

Journal:

Nature Reviews Drug Discovery

Year:

2012

Language:

english

File:

PDF, 641 KB

english, 2012

13

Proprotein convertase subtilisin / kexin 9 (PCSK9) inhibitors and the future of dyslipidemia therapy: an updated patent review (2011-2015)

Elbitar, Sandy, Khoury, Petra El, Ghaleb, Youmna, Rabès, Jean-Pierre, Varret, Mathilde, Seidah, Nabil G., Boileau, Catherine, Abifadel, Marianne

Journal:

Expert Opinion on Therapeutic Patents

Year:

2016

Language:

english

File:

PDF, 822 KB

english, 2016

14

Proprotein convertase subtilisin/kexin type 9 (PCSK9): Hepatocyte-specific low-density lipoprotein receptor degradation and critical role in mouse liver regeneration

Ahmed Zaid, Anna Roubtsova, Rachid Essalmani, Jadwiga Marcinkiewicz, Ann Chamberland, Josée Hamelin, Michel Tremblay, Hélène Jacques, Weijun Jin, Jean Davignon, Nabil G. Seidah, Annik Prat

Journal:

Year:

2008

Language:

english

File:

PDF, 3.19 MB

english, 2008

15

Implication of proprotein convertases in the processing and spread of severe acute respiratory syndrome coronavirus

Eric Bergeron, Martin J. Vincent, Louise Wickham, Josée Hamelin, Ajoy Basak, Stuart T. Nichol, Michel Chrétien, Nabil G. Seidah

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 987 KB

english, 2005

16

Amino acid sequence of rat submaxillary tonin reveals similarities to serine proteases

Lazure, Claude, Leduc, Richard, Seidah, Nabil G., Thibault, Gaétan, Genest, Jacques, Chrétien, Michel

Journal:

Year:

1984

File:

PDF, 465 KB

1984

17

Distribution and Regulation of Proconvertases PC1 and PC2 in Human Pituitary Adenomas

Long Jin, Elzbieta Kulig, Xiang Qian, Bernd W. Scheithauer, William F. Young, Dudley H. Davis, Nabil G. Seidah, Michel Chretien, Ricardo V. Lloyd

Journal:

Year:

1999

Language:

english

File:

PDF, 582 KB

english, 1999

18

Cellular processing of the neurotrophin precursors of NT3 and BDNF by the mammalian proprotein convertases

Nabil G. Seidah, Suzanne Benjannet, Sangeeta Pareek, Michel Chrétien, Richard A. Murphy

Journal:

Year:

1996

Language:

english

File:

PDF, 539 KB

english, 1996

19

Localization of the Human Prostatic Secretory Protein PSP94 and its mRNA in the Epithelial Cells of the Prostate

ANOOP BRAR, MAJAMBU MBIKAY, FRANCINE SIROIS, SYLVIE FOURNIER, NABIL G. SEIDAH, MICHEL CHRÉTIEN

Journal:

Journal of Andrology

Year:

1988

Language:

english

File:

PDF, 1.39 MB

english, 1988

20

Implication of the proprotein convertases in iron homeostasis: Proprotein convertase 7 sheds human transferrin receptor 1 and furin activates hepcidin

Guillemot, Johann, Canuel, Maryssa, Essalmani, Rachid, Prat, Annik, Seidah, Nabil G.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.11 MB

english, 2013

21

Proprotein Convertase Subtilisin/Kexin Type 9 Deficiency Reduces Melanoma Metastasis in Liver

Sun, Xiaowei, Essalmani, Rachid, Day, Robert, Khatib, Abdel M., Seidah, Nabil G., Prat, Annik

Journal:

Year:

2012

Language:

english

File:

PDF, 1.66 MB

english, 2012

22

Inhibitory Activity and Structural Characterization of a C-Terminal Peptide Fragment Derived from the Prosegment of the Proprotein Convertase PC7 †

Bhattacharjya, Surajit, Xu, Ping, Zhong, Mei, Chrétien, Michel, Seidah, Nabil G., Ni, Feng

Journal:

Year:

2000

Language:

english

File:

PDF, 373 KB

english, 2000

23

Lipoprotein(a) Catabolism Is Regulated by Proprotein Convertase Subtilisin/Kexin Type 9 through the Low Density Lipoprotein Receptor

Romagnuolo, Rocco, Scipione, Corey A., Boffa, Michael B., Marcovina, Santica M., Seidah, Nabil G., Koschinsky, Marlys L.

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 2.79 MB

english, 2015

24

Intestinal and Hepatic Cholesterol Carriers in Diabetic Psammomys obesus

Levy, Emile, Lalonde, Geneviève, Delvin, Edgard, Elchebly, Mounib, Précourt, Louis P., Seidah, Nabil G., Spahis, Schohraya, Rabasa-Lhoret, Rémi, Ziv, Ehud

Journal:

Year:

2010

Language:

english

File:

PDF, 523 KB

english, 2010

25

Modulation of Protease Activated Receptor 1 Influences Human Metapneumovirus Disease Severity in a Mouse Model

Aerts, Laetitia, Hamelin, Marie-Ève, Rhéaume, Chantal, Lavigne, Sophie, Couture, Christian, Kim, WooJin, Susan-Resiga, Delia, Prat, Annik, Seidah, Nabil G., Vergnolle, Nathalie, Riteau, Beatrice, Boiv

Journal:

Year:

2013

Language:

english

File:

PDF, 1.21 MB

english, 2013

26

Characterization of β-endorphin immunoreactive peptides in rat pituitary and brain by coupled gel and reversed-phase high-performance liquid chromatography

Michael Dennis, Claude Lazure, Nabil G. Seidah, Michel Chrétien

Journal:

Journal of Chromatography A

Year:

1983

Language:

english

File:

PDF, 773 KB

english, 1983

27

Coordinated Expression of β-Amyloid Precursor Protein and the Putative β-Secretase BACE and α-Secretase ADAM10 in Mouse and Human Brain

Mieczyslaw Marcinkiewicz, Nabil G. Seidah

Journal:

Journal of Neurochemistry

Year:

2000

Language:

english

File:

PDF, 548 KB

english, 2000

28

Light and electron microscopic localization of the N-terminal fragment of human pro-opiomelanocortin in the human pituitary gland and in neoplasms

R. Yoshiyuki Osamura, Keiichi Watanabe, Nabil G. Seidah, John S. D. Chan, Michel Chrétien

Journal:

Virchows Archiv

Year:

1985

Language:

english

File:

PDF, 582 KB

english, 1985

29

Precursor Convertases: An Evolutionary Ancient, Cell-Specific, Combinatorial Mechanism Yielding Diverse Bioactive Peptides and Proteins

NABIL G. SEIDAH, ROBERT DAY, MIECZYSLAW MARCINKIEWICZ, MICHEL CHRÉTIEN

Journal:

Annals of the New York Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 4.29 MB

english, 1998

30

N-linked glycosylation affects the processing of mouse submaxillary gland prorenin in transfected AtT20 cells

Ruth Graciela LADENHEIM, Nabil G. SEIDAH, François ROUGEON

Journal:

Year:

1991

Language:

english

File:

PDF, 814 KB

english, 1991

31

Increased stress-induced analgesia in mice lacking the proneuropeptide convertase PC2

Gilles Croissandeau, Flora Wahnon, Kiran Yashpal, Nabil G. Seidah, Terence J. Coderre, Michel Chrétien, Majambu Mbikay

Journal:

Neuroscience Letters

Year:

2006

Language:

english

File:

PDF, 275 KB

english, 2006

32

Metabolic clearance rate and half-time disappearance rate of human N-terminal and adrenocorticotropin of pro-opiomelanocortin in the rat: A comparative study

Chao-Lin Lu, John S.D. Chan, André De Léan, Andrew Chen, Nabil G. Seidah, Michel Chrétien

Journal:

Year:

1983

Language:

english

File:

PDF, 475 KB

english, 1983

33

Protease inhibitors suppress in vitro growth of human small cell lung cancer

David A. Clark, Robert Day, Nabil Seidah, Terry W. Moody, Frank Cuttitta, Thomas P. Davis

Journal:

Year:

1993

Language:

english

File:

PDF, 959 KB

english, 1993

34

The effect of insulin on circulating PCSK9 in postmenopausal obese women

Awan, Zuhier, Dubuc, Geneviève, Faraj, May, Dufour, Robert, Seidah, Nabil G., Davignon, Jean, Rabasa-Lhoret, Rémi, Baass, Alexis

Journal:

Clinical Biochemistry

Year:

2014

Language:

english

File:

PDF, 665 KB

english, 2014

35

Effects of pro-opiomelanocortin fragments on release of catecholamines from adrenal chromaffin cells

Boksa, Patricia, Seidah, Nabil G., Chrétien, Michel, Livett, Bruce G.

Journal:

Neuroscience Letters

Year:

1982

Language:

english

File:

PDF, 1.79 MB

english, 1982

36

Effect of N-Terminal Portion of Pro-opiomelanocortin on Aldosterone Release by Human Adrenal Adenoma in Vitro *

LIS, MARTIN, HAMET, PAVEL, GUTKOWSKA, JOLANTA, MAURICE, GINETTE, SEIDAH, NABIL G., LARIVIÉRE, NORMAND, CHRÉTIEN, MICHEL, GENEST, JACQUES

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

1981

Language:

english

File:

PDF, 475 KB

english, 1981

37

Deletion of Mbtps1 (PCSK8, S1P, SKI-1) in Osteocytes Stimulates Soleus Muscle Regeneration and Increased Size and Contractile Force with Age

Gorski, Jeff P., Huffman, Nichole T., Vallejo, Julian, Brotto, Leticia, Chittur, Sridar V., Breggia, Anne, Stern, Amber, Huang, Jian, Mo, Chenglin, Seidah, Nabil G., Bonewald, Lynda, Brotto, Marco

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 2.63 MB

english, 2015

38

A case of hypocholesterolemia and steatosis in a carrier of a PCSK9 loss-of-function mutation and polymorphisms predisposing to nonalcoholic fatty liver disease

Di Filippo, Mathilde, Vokaer, Benoit, Seidah, Nabil G.

Journal:

Journal of Clinical Lipidology

Year:

2017

Language:

english

File:

PDF, 388 KB

english, 2017

39

Osteopontin as a novel substrate for the proprotein convertase 5/6 ( PCSK5 ) in bone

Hoac, Betty, Susan-Resiga, Delia, Essalmani, Rachid, Marcinkiweicz, Edwige, Seidah, Nabil G., McKee, Marc D.

Journal:

Year:

2018

Language:

english

File:

PDF, 2.31 MB

english, 2018

40

Posttranslational modification of proprotein convertase subtilisin/kexin type 9 is differentially regulated in response to distinct cardiometabolic treatments as revealed by targeted proteomics

Gauthier, Marie-Soleil, Awan, Zuhier, Bouchard, Annie, Champagne, Josée, Tessier, Sylvain, Faubert, Denis, Chabot, Katherine, Garneau, Pierre Y., Rabasa-Lhoret, Rémi, Seidah, Nabil G., Ridker, Paul M.

Journal:

Journal of Clinical Lipidology

Year:

2018

Language:

english

File:

PDF, 2.49 MB

english, 2018

41

In utero Measurement of Heart Rate in Mouse by Noninvasive M-mode Echocardiography

Kim, WooJin, Seidah, Nabil G., Prat, Annik

Journal:

Journal of Visualized Experiments

Year:

2013

Language:

english

File:

PDF, 714 KB

english, 2013

42

Three common alleles of KIR2DL4 (CD158d) encode constitutively expressed, inducible and secreted receptors in NK cells

Jodie P. Goodridge, Louise J. Lathbury, Noriko K. Steiner, Christine N. Shulse, Philomena Pullikotil, Nabil G. Seidah, Carolyn K. Hurley, Frank T. Christiansen, Campbell S. Witt

Journal:

European Journal of Immunology

Year:

2007

Language:

english

File:

PDF, 410 KB

english, 2007

43

Inhibition of HIV-2ROD replication in a lymphoblastoid cell line by the α1-antitrypsin Portland variant (α1-PDX) and the decRVKRcmk peptide: comparison with HIV-1LAI

Bouchaib Bahbouhi, Mourad Bendjennat, Cristina Chiva, Marcelo Kogan, Fernando Albericio, Ernest Giralt, Nabil Georges Seidah, Elmostafa Bahraoui

Journal:

Microbes and Infection

Year:

2001

Language:

english

File:

PDF, 422 KB

english, 2001

44

The Subtilisin/Kexin Family of Precursor Convertases: Emphasis on PC1, PC2/7B2, POMC and the Novel Enzyme SKI-1

NABIL G. SEIDAH, SUZANNE BENJANNET, JOSÉE HAMELIN, AIDA M. MAMARBACHI, AJOY BASAK, JADWIGA MARCINKIEWICZ, MAJAMBU MBIKAY, MICHEL CHRÉTIEN, MIECZYSLAW MARCINKIEWICZ

Journal:

Annals of the New York Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.93 MB

english, 1999

45

Characterization of a repressor element in the promoter region of proprotein convertase 2 (PC2) gene

Majambu Mbikay, Marie-Laure Raffin-Sanson, Francine Sirois, Luaba Kalenga, Michel Chrétien, Nabil G. Seidah

Journal:

Molecular Brain Research

Year:

2002

Language:

english

File:

PDF, 2.05 MB

english, 2002

46

APOE p.Leu167del mutation in familial hypercholesterolemia

Awan, Zuhier, Choi, Hong Y., Stitziel, Nathan, Ruel, Isabelle, Bamimore, Mary Aderayo, Husa, Regina, Gagnon, Marie-Helene, Wang, Rui-Hao L., Peloso, Gina M., Hegele, Robert A., Seidah, Nabil G., Kathi

Journal:

Atherosclerosis

Year:

2013

Language:

english

File:

PDF, 1.25 MB

english, 2013

47

Impaired Fertility in Mice Deficient for the Testicular Germ-Cell Protease PC4

Majambu Mbikay, Haidy Tadros, Norito Ishida, Charlie P. Lerner, Eve De Lamirande, Andrew Chen, Mohamed El-Alfy, Yves Clermont, Nabil G. Seidah, Michel Chrétien, Claude Gagnon and Elizabeth M. Simpson

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.00 MB

english, 1997

48

Structure of the carboxyl propeptide of chicken type II procollagen determined by DNA and protein sequence analysis

Ninomiya, Yoshifumi, Showalter, Allan M., Van der Rest, Michel, Seidah, Nabil G., Chretien, Michel, Olsen, Bjorn R.

Journal:

Year:

1984

Language:

english

File:

PDF, 1.02 MB

english, 1984

49

Potential Role of Proprotein Convertase SKI-1 in the Mineralization of Primary Bone

Gorski, Jeff P., Huffman, Nichole T., Cui, Chaoying, Henderson, Ellen P., Midura, Ronald J., Seidah, Nabil G.

Journal:

Cells Tissues Organs

Year:

2009

Language:

english

File:

PDF, 281 KB

english, 2009

50

Proparathyroid Hormone Processing by the Proprotein Convertase-7: Comparison with Furin and Assessment of Modulation of Parathyroid Convertase Messenger Ribonucleic Acid Levels by Calcium and 1,25-Dihydroxyvitamin D 31

Canaff, Lucie, Bennett, Hugh P. J., Hou, Yu, Seidah, Nabil G., Hendy, Geoffrey N.

Journal:

Year:

1999

Language:

english

File:

PDF, 980 KB

english, 1999

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